HCG
HCG (Human Chorionic Gonadotropin) (Research Peptide)
For Research Use Only – Not for Human Consumption, Diagnostic, or Therapeutic Use. HCG is supplied strictly for laboratory and scientific research applications, such as in vitro and in vivo studies on luteinizing hormone (LH) receptor activation, testosterone production, Leydig cell function, fertility models, and hypothalamic-pituitary-gonadal (HPG) axis regulation. All information below is for educational and research reference only.
What Is HCG?
Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone naturally produced during pregnancy. In research settings, it is used as a potent analogue of luteinizing hormone (LH) due to its structural similarity and longer half-life.
Typically supplied as a lyophilized powder for reconstitution in research settings.
Mechanism of Action (Research Context)
In laboratory models, HCG binds to the LH/CG receptor (LHCGR) on Leydig cells in the testes (and theca cells in ovaries). This activation stimulates:
Increased cyclic AMP (cAMP) production
Testosterone synthesis and secretion from Leydig cells
Spermatogenesis support in male models
Progesterone production in female models
Because of its longer half-life compared to native LH, HCG is often studied for its ability to sustain gonadal stimulation.
Key Research Findings and Potential Areas of Study
Preclinical and clinical-stage research explores HCG in:
Maintenance of testosterone levels during suppression models
Fertility and spermatogenesis studies
Hypogonadism and HPG axis recovery models
Leydig cell function and steroidogenesis pathways
It is a standard tool for investigating gonadal hormone regulation and reproductive endocrinology.
Research Considerations
HCG is commonly studied via subcutaneous or intramuscular administration in animal models. Researchers monitor testosterone levels, testicular weight, sperm parameters, and downstream steroidogenic markers. Dosing is typically expressed in International Units (IU).
Storage for Research: Lyophilized powder is stable at –20°C or refrigerated. Reconstituted solutions should follow standard peptide handling protocols and be used promptly.
Why Researchers Choose HCG
HCG is a reliable and well-characterized research compound for studying LH receptor signaling, testosterone production, and reproductive axis recovery. It is particularly useful in models involving steroid suppression, fertility preservation, or endocrine disruption.
Questions about specifications, COA, or research applications? Contact our support team.
All products are for research purposes only. Not intended for human use.
