Testagen
Testagen (KEDG) (Research Peptide)
For Research Use Only – Not for Human Consumption, Diagnostic, or Therapeutic Use.
Testagen is supplied strictly for laboratory and scientific research applications, such as in vitro and in vivo studies on peptide bioregulators, epigenetic regulation, hypothalamic-pituitary-gonadal (HPG) axis signaling, testicular cell function, and short-peptide nuclear interactions. All information below is for educational and research reference only.
What Is Testagen?
Testagen is a synthetic tetrapeptide bioregulator with the sequence Lys-Glu-Asp-Gly (KEDG). It belongs to the class of ultrashort peptides developed in the Khavinson bioregulator research program and is studied for its potential tissue-specific regulatory effects.
Molecular Formula: C₁₇H₂₉N₅O₉
Molecular Weight: ≈ 447.44 Da
CAS Number: 1026993-38-3
Sequence: Lys-Glu-Asp-Gly (KEDG / H-Lys-Glu-Asp-Gly-OH)
Typically supplied as a lyophilized powder for reconstitution in research settings.
Mechanism of Action (Research Context)
In laboratory models, Testagen is investigated for its ability to penetrate cellular and nuclear membranes. Research on related short peptides suggests possible interactions with histones and DNA, which may influence gene expression patterns. Proposed research pathways include modulation of pituitary and gonadal signaling, although the exact molecular targets and downstream effects continue to be explored.
Key Research Areas
Preclinical studies (primarily from the originating research groups) have examined Testagen in models related to:
Peptide bioregulation of the HPG axis
Testicular tissue and Leydig cell function
Pituitary signaling (including TSH-related pathways in certain animal models)
Short-peptide nuclear entry, histone binding, and epigenetic regulation
Cellular differentiation and gene expression studies
Note: Independent, large-scale replication of specific endocrine outcomes remains limited in the broader peer-reviewed literature.
Research Considerations
Testagen is commonly studied via systemic or local administration in animal models or added to cell cultures. Researchers typically monitor gene expression, hormone-related markers, tissue morphology, and cellular penetration/localization.
Storage for Research: Lyophilized powder is stable at –20°C. Reconstituted solutions should follow standard peptide handling protocols.
Why Researchers Choose Testagen
Testagen is of interest as a short-chain bioregulator peptide for investigating organ-specific peptide signaling, nuclear peptide interactions, and potential epigenetic effects on endocrine tissues. Its small size and reported cellular penetration make it a useful tool in ultrashort-peptide and bioregulator research.
Questions about specifications, COA, or research applications? Contact our support team.
All products are for research purposes only. Not intended for human use.
